Description
Product Characteristics:
Aliases: NACA2 antibody, NACAL antibody, Nascent polypeptide-associated complex subunit alpha-2 antibody, Alpha-NAC-like antibody, Hom s 2.01 antibody, Nascent polypeptide-associated complex subunit alpha-like antibody, NAC-alpha-like antibody
Target Information: Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites) (By similarity)